Recombinant PCNA Monoclonal Antibody
Product Specifications
Background
Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves its processivity by encircling the DNA, where it acts as a scaffold to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling and epigenetics. PCNA gene is often stably and constitutively expressed in most tissues and cells, it is commonly used as a loading control for western blot and other test.
Abbreviation
PCNA
UniProt
P12004
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human PCNA Protein
Target
MGC; ATLD; etID36690.; HGCN; fa28e; fb36g; PCNA; ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; Pcna/cyclin; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; MGC8367; Mutagen-sensitive 209 protein; OTTHUMP00000030189; OTTHUMP00000030190; PCNA; Pcna/cyclin; PCNAR; Polymerase delta accessory protein; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03
Clonality
Monoclonal
Clone
3G2
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Tags & Cell Markers; Cancer; Isotype; Loading Controls
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
29 kDa
Observed Molecular Weight
35 kDa
Isotype
IgG
Curated Selection
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