Recombinant IkB alpha/NFKBIA Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Abbreviation
NFKBIA
UniProt
P25963
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human IkB alpha/NFKBIA Protein
Target
EDAID; MAD; IKBA; MAD-3; NFKBI; IKB alpha; NFKBIA; EDAID2; I kappa B alpha; IkappaBalpha; I-kappa-B-alpha; IKBalpha; IkB-alpha; MAD 3; NF kappa B inhibitor alpha; MAD3; alpha; Major histocompatibility complex enhancer-binding protein MAD3; NF-kappa-B inhibitor alpha; Nuclear factor of kappa light chain gene enhancer in B cells; Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; pIκBα
Clonality
Monoclonal
Clone
5D10
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Cancer; Immunology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IP 1-4 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/1g06YKv3
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
38 kDa
Isotype
IgG
Curated Selection
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