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Recombinant c-Kit/CD117 Monoclonal Antibody

Product Specifications

Background

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Abbreviation

KIT

UniProt

P10721

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human c-Kit/CD117 protein

Target

KIT; C-Kit; CD117; PBT; SCFR; Mast/stem cell growth factor receptor Kit; p145 c-kit; Piebald trait protein; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; SCFR; C Kit; CD_antigen: CD117; c-Kit Ligand; Kit Ligand; KIT oncogene; KIT proto oncogene receptor tyrosine kinase; KIT proto-oncogene receptor tyrosine kinase; Mast cell growth factor receptor; MGF; Proto oncogene c Kit; Proto oncogene tyrosine protein kinase Kit; SCF Receptor; soluble KIT variant 1; Steel Factor Receptor; Stem cell factor receptor; tyrosine protein kinase Kit; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog; v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein

Clonality

Monoclonal

Clone

5D9

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Immunology; Tags & Cell Markers; Signal Transduction; Neuroscience; Stem Cells; Cancer; Developmental Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

Available Sizes

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