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Recombinant HIF-1 alpha/HIF1A Monoclonal Antibody

Product Specifications

Background

The hypoxia-inducible transcription factor 1 alpha (HIF-1 alpha) is the regulated member of the transcription factor heterodimer HIF-1. HIF-1 binds to hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, which illustrates the broad impact of gene regulation by HIF-1 alpha.

Abbreviation

HIF1A

UniProt

Q16665

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human HIF-1 alpha/HIF1A Protein

Target

HIF; MOP; PASD; member of PAS protein; hypoxia inducible factor; bHLHe; HIF-1A; HIF1-ALPHA; HIF-1alpha; HIF1A; bHLHe78; HIF1; MOP1; PASD8; HIF-1-alpha; hypoxia inducible factor 1; alpha subunit; basic helix-loop-helix transcription factor; hypoxia-inducible factor 1-alpha; HIF 1alpha; member of PAS protein 1; ARNT interacting protein; ARNT-interacting prot; alpha subunit (basic helix loop helix transcription factor) ; ARNT-interacting protein; Basic helix loop helix PAS protein MOP1; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; HIF 1A; HIF1 A; HIF1 Alpha; Hypoxia inducible factor 1 alpha; Hypoxia inducible factor 1 alpha isoform I.3; Hypoxia inducible factor 1 alpha subunit; Hypoxia inducible factor 1 alpha subunit basic helix loop helix transcription factor; Hypoxia inducible factor1alpha; Member of PAS superfamily 1; Member of the PAS Superfamily 1; MOP 1; PAS domain-containing protein 8; PASD 8

Clonality

Monoclonal

Clone

5D7

Conjugation

Unconjugated

Applications

ICC/IF

Field of Research

Cardiovascular; Epigenetics and Nuclear Signaling; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

111 kDa

Observed Molecular Weight

111 kDa

Isotype

IgG

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