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Recombinant Tryptophan Hydroxylase 1/TPH1 Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Abbreviation

TPH1

UniProt

P17752

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein

Target

TPH1; TPRH; TRPH; TPH; tryptophan 5-monooxygenase; Tryptophan hydroxylase 1

Clonality

Monoclonal

Clone

5D6

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Signal Transduction; Neuroscience; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

55 kDa

Observed Molecular Weight

55 kDa

Isotype

IgG

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