Recombinant Tryptophan Hydroxylase 1/TPH1 Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Abbreviation
TPH1
UniProt
P17752
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Tryptophan Hydroxylase 1/TPH1 Protein
Target
TPH1; TPRH; TRPH; TPH; tryptophan 5-monooxygenase; Tryptophan hydroxylase 1
Clonality
Monoclonal
Clone
5D6
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Signal Transduction; Neuroscience; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IP 0.2-1 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
55 kDa
Observed Molecular Weight
55 kDa
Isotype
IgG
Curated Selection
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