Recombinant Phospho-Src (Tyr530) Monoclonal Antibody
Product Specifications
Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Abbreviation
SRC
UniProt
P12931
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around
Target
THC; ASV; SRC1; THC6; c-SRC; p60-Src; SRC; pp60c-src; Proto-oncogene c-Src; Proto-oncogene tyrosine-protein kinase Src; Avian sarcoma virus; c SRC; CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA; cSrc; EC 2.7.10.2; Neuronal CSRC tyrosine specific protein kinase; Neuronal SRC; Oncogene SRC; OTTHUMP00000174476; OTTHUMP00000174477; p60 Src; p60Src; pp60c src; pp60csrc; Proto oncogene tyrosine protein kinase Src; Protooncogene SRC; Protooncogene SRC Rous sarcoma; SRC Oncogene; SRC proto oncogene non receptor tyrosine kinase; Tyrosine kinase pp60c src; Tyrosine protein kinase SRC 1; Tyrosine protein kinase SRC1; v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog; V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) ; v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian
Clonality
Monoclonal
Clone
11G10
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Epigenetics and Nuclear Signaling; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:10000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/4pPgNEvz
Calculated Molecular Weight
60 kDa
Observed Molecular Weight
60 kDa
Isotype
IgG
Available Sizes
Curated Selection
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