Recombinant Phospho-VEGF Receptor 2 (Tyr1175) Monoclonal Antibody
Product Specifications
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Abbreviation
KDR
UniProt
P35968
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around Tyr1175 of Human Phospho-VEGF Receptor 2
Target
Krd; VEGF Receptor; Fetal liver kinase; Protein-tyrosine kinase receptor flk; Vascular endothelial growth factor receptor; sVEGFR; VEGF R;6130401C; FLK; CD309; FLK1; VEGFR; VEGFR2; VEGF Receptor 2; KDR;6130401C07; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Krd-1; Ly73; Protein-tyrosine kinase receptor flk-1; sVEGFR-2; Vascular endothelial growth factor receptor 2; VEGF R2; VEGFR-2; KDR
Clonality
Monoclonal
Clone
11G9
Conjugation
Unconjugated
Applications
WB
Field of Research
Cardiovascular; Microbiology; Signal Transduction; Stem Cells; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:10000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
152 kDa
Observed Molecular Weight
280 kDa
Isotype
IgG
Available Sizes
Curated Selection
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