Recombinant Phospho-Paxillin (Tyr118) Monoclonal Antibody
Product Specifications
Background
This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion) . Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445) .
Abbreviation
PXN
UniProt
P49023
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues around Tyr118 of the Human Phospho-Paxillin
Target
Paxillin; PXN; entrez:5829
Clonality
Monoclonal
Clone
11G8
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
65 kDa
Observed Molecular Weight
68 kDa
Isotype
IgG
Available Sizes
Curated Selection
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