Recombinant Phospho-Tau (Thr217) Monoclonal Antibody
Product Specifications
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Abbreviation
MAPT
UniProt
P10636
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau
Target
FTDP; PPP1R; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; pMAPT/pTAU; TAU and MAPT; N/A; AI413597; AW045860; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; included; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Mtapt; Paired helical filament tau; PHF tau; Protein phosphatase 1; pTau; regulatory subunit 103; RNPTAU; Tauopathy and respiratory failure
Clonality
Monoclonal
Clone
6H8
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:5000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/TPVa9OrO
Calculated Molecular Weight
46 kDa
Observed Molecular Weight
50-70 kDa
Isotype
IgG
Available Sizes
Curated Selection
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