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Recombinant Phospho-Tau (Thr217) Monoclonal Antibody

Product Specifications

Background

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Abbreviation

MAPT

UniProt

P10636

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau

Target

FTDP; PPP1R; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; MAPT; Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; pMAPT/pTAU; TAU and MAPT; N/A; AI413597; AW045860; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; included; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau; Microtubule associated protein tau isoform 4; Mtapt; Paired helical filament tau; PHF tau; Protein phosphatase 1; pTau; regulatory subunit 103; RNPTAU; Tauopathy and respiratory failure

Clonality

Monoclonal

Clone

6H8

Conjugation

Unconjugated

Applications

WB

Field of Research

Neuroscience; Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:5000

Buffer

10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

46 kDa

Observed Molecular Weight

50-70 kDa

Isotype

IgG

Available Sizes

Curated Selection

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