Recombinant Phospho-MEK1/2 (Ser217, 2210) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Abbreviation
MAP2K1
UniProt
Q02750
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues around Ser218 and Ser222 of the Human MEK1
Target
MEK; MKK; CFC; MAPKK; PRKMK; MAP2K; CFC3; MAPKK1; MEK1; MKK1; PRKMK1; MAP2K1; Dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAPK/ERK kinase 1; MAPKK 1; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MP2K1; Protein kinase mitogen activated; Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1)
Clonality
Monoclonal
Clone
11A4
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:2000-1:20000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
43 kDa
Observed Molecular Weight
43 kDa
Isotype
IgG
Available Sizes
Curated Selection
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