Recombinant Phospho-ERK1/2 (Thr202, Tyr204) Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Abbreviation
MAPK3
UniProt
P27361
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic phosphopeptide corresponding to residues around Thr202, Tyr204 of Human Phospho-ERK1/2.
Target
ERT; PRKM; MAPK; P44ERK; p44-ERK; ERK; ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK; MAPK3; ERK 1; ERT 2; Extracellular Signal Regulated Kinase 1; Extracellular signal related kinase 1; Extracellular signal-regulated kinase 1; HGNC6877; Insulin Stimulated MAP2 Kinase; Insulin-stimulated MAP2 kinase; MAP Kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAPK 1; MAPK 3; MAPK1; MGC20180; Microtubule Associated Protein 2 Kinase; Microtubule-associated protein 2 kinase; Mitogen Activated Protein Kinase 3; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 3; MK03; OTTHUMP00000174538; OTTHUMP00000174541; p44 ERK1; p44 MAPK; PRKM 3; Protein Kinase Mitogen Activated 3
Clonality
Monoclonal
Clone
11A1
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Stem Cells; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:1000-1:20000
Buffer
10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/Z6SdyIyM
Calculated Molecular Weight
41 kDa
Observed Molecular Weight
41 kDa
Isotype
IgG
Available Sizes
Curated Selection
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