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Recombinant Phospho-p70 S6 Kinase 1 (Thr389) Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Abbreviation

RPS6KB1

UniProt

P23443

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phosphopeptide corresponding to residues around Thr389 of human p70 S6 kinase 1.

Target

RPS6KB; S6K-beta; PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70 (S6K) -alpha; p70-S6K; p70-alpha; P70 S6K; RPS6KB1; p70S6KA;70 kDa ribosomal protein S6 kinase 1; alpha 1; alpha 2; KS6B1; p70 alpha; P70 beta 1; p70 ribosomal S6 kinase alpha; p70 ribosomal S6 kinase beta 1; P70 S6 Kinase; p70 S6 kinase alpha; p70 S6K-alpha; p70 (S6K) alpha; P70S6K; p70-S6K 1; P70S6K1; p70S6Kb; Ribosomal protein S6 kinase 70kDa polypeptide 1; Ribosomal protein S6 kinase beta 1; Ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; Serine/threonine kinase 14 alpha; Serine/threonine-protein kinase 14A

Clonality

Monoclonal

Clone

12G12

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:1000-1:200000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

59 kDa

Observed Molecular Weight

60 kDa,80 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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