Recombinant GCG/Glucagon Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Abbreviation
GCG
UniProt
P01275
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the Human GCG/Glucagon
Target
GLP; GCG; GLP-1; GLP1; GLP2; GRPP; glucagon; Glicentin-Related Polypeptide; GLP-1 (7-36) ; GLP-1 (7-37) ; Glucagon-like peptide 1; Glucagon-Like Peptide 2; Incretin hormone; Pro-glucagon; Glicentin; Oxyntomodulin; OXM; OXY; GLP-2; GLP 1; GCG; Glucagon
Clonality
Monoclonal
Clone
12G6
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Signal Transduction; Stem Cells; Cancer; Developmental Biology; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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