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Recombinant GCG/Glucagon Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Abbreviation

GCG

UniProt

P01275

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the Human GCG/Glucagon

Target

GLP; GCG; GLP-1; GLP1; GLP2; GRPP; glucagon; Glicentin-Related Polypeptide; GLP-1 (7-36) ; GLP-1 (7-37) ; Glucagon-like peptide 1; Glucagon-Like Peptide 2; Incretin hormone; Pro-glucagon; Glicentin; Oxyntomodulin; OXM; OXY; GLP-2; GLP 1; GCG; Glucagon

Clonality

Monoclonal

Clone

12G6

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Signal Transduction; Stem Cells; Cancer; Developmental Biology; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

Available Sizes

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