Recombinant MESDC2 Monoclonal Antibody
Product Specifications
Background
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.
Abbreviation
MESD
UniProt
Q14696
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human MESDC2 protein
Target
UNQ; PRO; KIAA; MESDC; MESDC2; BOCA; MESD; KIAA0081; MESDM; UNQ1911; PRO4369
Clonality
Monoclonal
Clone
11D16
Conjugation
Unconjugated
Applications
WB; ICC/IF; IP
Field of Research
Stem Cells; Developmental Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; ICC/IF 1:20-1:100; IP 1-4 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
26 kDa
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
