Recombinant MESDC2 Monoclonal Antibody

Product Specifications

Background

Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.

Abbreviation

MESD

UniProt

Q14696

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human MESDC2 protein

Target

UNQ; PRO; KIAA; MESDC; MESDC2; BOCA; MESD; KIAA0081; MESDM; UNQ1911; PRO4369

Clonality

Monoclonal

Clone

11D16

Conjugation

Unconjugated

Applications

WB; ICC/IF; IP

Field of Research

Stem Cells; Developmental Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; ICC/IF 1:20-1:100; IP 1-4 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.