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Recombinant DOPA Decarboxylase/DDC Monoclonal Antibody

Product Specifications

Background

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) . AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Abbreviation

DDC

UniProt

P20711

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human DOPA Decarboxylase/DDC protein

Target

DDC; AADC; Aromatic L Amino Acid Decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC_HUMAN; DOPA decarboxylase; DOPA decarboxylase (aromatic L-amino acid decarboxylase)

Clonality

Monoclonal

Clone

6A1

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Neuroscience; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

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