Recombinant DOPA Decarboxylase/DDC Monoclonal Antibody
Product Specifications
Background
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) . AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Abbreviation
DDC
UniProt
P20711
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human DOPA Decarboxylase/DDC protein
Target
DDC; AADC; Aromatic L Amino Acid Decarboxylase; Aromatic-L-amino-acid decarboxylase; DDC_HUMAN; DOPA decarboxylase; DOPA decarboxylase (aromatic L-amino acid decarboxylase)
Clonality
Monoclonal
Clone
6A1
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Neuroscience; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/cyXWbo06
Isotype
IgG
Curated Selection
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