Recombinant Cathepsin L1/CTSL1 Monoclonal Antibody

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Hgg; MGC; wu:fb30g; CTSL; CATL; CTSL1; MEP;1 b; Cathepsin L1 light chain; CathepsinL; CATL1; cb15; ctsl1b; FLJ31037; hgg1; MGC123162; wu:fb30g09; Procathepsin L; Cathepsin L1; Major excreted protein; Cathepsin L

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.