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Recombinant Lipocalin-2/LCN2 Monoclonal Antibody

Product Specifications

Background

This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.

Abbreviation

LCN2

UniProt

P80188

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Lipocalin-2/LCN2 Protein

Target

LCN;24p; Oncogene 24p; Siderocalin LCN;25 kDa alpha-2-microglobulin-related subunit of MMP; LCN2;24p3; MSFI; NGAL; p25;25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin 2; Lipocalin-2; Neutrophil gelatinase-associated lipocalin; Oncogene 24p3; Siderocalin LCN2; HNL; Lipocalin 2; MSFI; Oncogene 24p3;25 kDa alpha 2 microglobulin related subunit of MMP9; Alpha 2 microglobulin related protein; HGNC:6526; Lcn 2; Migration stimulating factor inhibitor; Neutrophil gelatinase associated lipocalin; Neutrophil gelatinase associated lipocalin precursor; Oncogenic lipocalin 24p3; Siderocalin; SV40 induced 24P3 protein; Uterocalin

Clonality

Monoclonal

Clone

7F10

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Immunology; Cardiovascular; Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

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