Recombinant Lipocalin-2/LCN2 Monoclonal Antibody
Product Specifications
Background
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
Abbreviation
LCN2
UniProt
P80188
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human Lipocalin-2/LCN2 Protein
Target
LCN;24p; Oncogene 24p; Siderocalin LCN;25 kDa alpha-2-microglobulin-related subunit of MMP; LCN2;24p3; MSFI; NGAL; p25;25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin 2; Lipocalin-2; Neutrophil gelatinase-associated lipocalin; Oncogene 24p3; Siderocalin LCN2; HNL; Lipocalin 2; MSFI; Oncogene 24p3;25 kDa alpha 2 microglobulin related subunit of MMP9; Alpha 2 microglobulin related protein; HGNC:6526; Lcn 2; Migration stimulating factor inhibitor; Neutrophil gelatinase associated lipocalin; Neutrophil gelatinase associated lipocalin precursor; Oncogenic lipocalin 24p3; Siderocalin; SV40 induced 24P3 protein; Uterocalin
Clonality
Monoclonal
Clone
7F10
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Immunology; Cardiovascular; Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
Curated Selection
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