IL3 Monoclonal Antibody
Product Specifications
Background
IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Abbreviation
IL3
UniProt
P04823
Host
Mouse
Reactivity
Rat
Immunogen
Recombinant Rat IL3 Protein
Target
MCGF; MCSF; MULTI-CSF; P-Cell Stimulating Factor; Il-3; Il3
Clonality
Monoclonal
Clone
11B11
Conjugation
Unconjugated
Applications
WB; IP
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IP 5-10 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/x7QJi4Ey
Calculated Molecular Weight
17 kDa
Observed Molecular Weight
17 kDa
Isotype
IgG1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items