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IL3 Monoclonal Antibody

Product Specifications

Background

IL3 (interleukin 3), also known as IL-3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL3/IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL3/IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL3/IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.

Abbreviation

IL3

UniProt

P04823

Host

Mouse

Reactivity

Rat

Immunogen

Recombinant Rat IL3 Protein

Target

MCGF; MCSF; MULTI-CSF; P-Cell Stimulating Factor; Il-3; Il3

Clonality

Monoclonal

Clone

11B11

Conjugation

Unconjugated

Applications

WB; IP

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 5-10 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Product MSDS

https://789.bio/eb/x7QJi4Ey

Calculated Molecular Weight

17 kDa

Observed Molecular Weight

17 kDa

Isotype

IgG1

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