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Interleukin-2/IL-2 Monoclonal Antibody

Product Specifications

Background

IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c) . IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.

Abbreviation

IL2

UniProt

P17108

Host

Mouse

Reactivity

Rat

Immunogen

Recombinant Rat Interleukin-2/IL-2 protein

Target

POIL; Aldesleukin; Interleukin-2; Involved in regulation of T cell clonal expansion; POIL2; T-cell growth factor; IL 2; IL2; lymphokine; TCGF; interleukin 2; T cell growth factor; Il-2

Clonality

Monoclonal

Clone

11B3

Conjugation

Unconjugated

Applications

IHC-P

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG2b

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