Interleukin-2/IL-2 Monoclonal Antibody
Product Specifications
Background
IL-2 (Interleukin 2) is a critical cytokine in T cell biology. It promotes T cell activation and expansion, the development, maintenance and function of regulatory T cells (Treg), and the differentiation of CD8+ T cells into terminal effector cells and memory cells. IL-2 signals through a receptor complex composed of CD25/IL-2 R alpha, IL-2 R beta, and the Common gamma Chain (gamma c) . IL-2 R beta is also a component of the IL-15 receptor complex. Gamma c is also a signaling subunit in the receptors for IL-4, -7, -9, -15, and -21.
Abbreviation
IL2
UniProt
P17108
Host
Mouse
Reactivity
Rat
Immunogen
Recombinant Rat Interleukin-2/IL-2 protein
Target
POIL; Aldesleukin; Interleukin-2; Involved in regulation of T cell clonal expansion; POIL2; T-cell growth factor; IL 2; IL2; lymphokine; TCGF; interleukin 2; T cell growth factor; Il-2
Clonality
Monoclonal
Clone
11B3
Conjugation
Unconjugated
Applications
IHC-P
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:50-1:200
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/i0z1xuCy
Isotype
IgG2b
Curated Selection
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