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CMPK1 Monoclonal Antibody

Product Specifications

Background

CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.

Abbreviation

CMPK1

UniProt

P30085

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CMPK1 protein

Target

CK; UMP-CMPK; CMK; CMPK; UCK; UMK; UMPK; CMPK1; CMPK 1; Cytidine monophosphate (UMP CMP) kinase 1 cytosolic; Cytidine monophosphate kinase; Cytidine monophosphate UMP CMP kinase 1 cytosolic; Cytidylate kinase; dCMP kinase; Deoxycytidylate kinase; EC 2.7.4.14; KCY; Monophosphatase kinase; OTTHUMP00000009565; RP11 511I2.1; UMP CMP; UMP CMP kinase; UMP/CMP kinase; UMP/CMPK; UMP-CMP kinase; Uridine monophosphate kinase; Uridine monophosphate/cytidine monophosphate kinase

Clonality

Monoclonal

Clone

2D13

Conjugation

Unconjugated

Applications

ICC/IF

Field of Research

Epigenetics and Nuclear Signaling; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

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