SerpinB3 Monoclonal Antibody
Product Specifications
Background
Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH (2) -terminal kinase (JNK1) .
Abbreviation
SERPINB3
UniProt
P29508
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human SerpinB3 Protein
Target
HsT; SSCA; Member; SERPINB; serpin B; SERPINB3; HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A; serpin B3; Clade B (ovalbumin) ; Member 3; Serpin Peptidase Inhibitor; SCCA; Serpin Peptidase Inhibitor; T4-A; clade B (ovalbumin) ; Clade B (ovalbumin) ; Protein T4-A; serine (or cysteine) proteinase inhibitor; Squamous cell carcinoma antigen 1
Clonality
Monoclonal
Clone
5B2
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product MSDS
https://789.bio/eb/jPZS9jsf
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG2a
Curated Selection
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