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SerpinB3 Monoclonal Antibody

Product Specifications

Background

Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH (2) -terminal kinase (JNK1) .

Abbreviation

SERPINB3

UniProt

P29508

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human SerpinB3 Protein

Target

HsT; SSCA; Member; SERPINB; serpin B; SERPINB3; HsT1196; SCC; SCCA-1; SCCA-PD; SCCA1; SSCA1; T4-A; serpin B3; Clade B (ovalbumin) ; Member 3; Serpin Peptidase Inhibitor; SCCA; Serpin Peptidase Inhibitor; T4-A; clade B (ovalbumin) ; Clade B (ovalbumin) ; Protein T4-A; serine (or cysteine) proteinase inhibitor; Squamous cell carcinoma antigen 1

Clonality

Monoclonal

Clone

5B2

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

45 kDa

Observed Molecular Weight

45 kDa

Isotype

IgG2a

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