SerpinB1/ELANH2 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
Abbreviation
SerpinB1
UniProt
P30740
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human SerpinB1/ELANH2 protein
Target
HEL; Peptidase inhibitor; ELANH; HEL-S; SERPINB; SERPINB1; EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2; Leukocyte elastase inhibitor; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2
Clonality
Monoclonal
Clone
3G11
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Cardiovascular; Cell Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; IP 1-2 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
43 kDa
Observed Molecular Weight
43 kDa
Isotype
IgG1
Curated Selection
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