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SerpinB1/ELANH2 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.

Abbreviation

SerpinB1

UniProt

P30740

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human SerpinB1/ELANH2 protein

Target

HEL; Peptidase inhibitor; ELANH; HEL-S; SERPINB; SERPINB1; EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2; Leukocyte elastase inhibitor; Monocyte/neutrophil elastase inhibitor; Peptidase inhibitor 2

Clonality

Monoclonal

Clone

3G11

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cardiovascular; Cell Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; IP 1-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

43 kDa

Observed Molecular Weight

43 kDa

Isotype

IgG1

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