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Cystatin A/CSTA Monoclonal Antibody

Product Specifications

Background

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Abbreviation

CSTA

UniProt

P01040

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human Cystatin A/CSTA protein

Target

PSS; STF; CSTA; AREI; PSS4; STF1; STFA; Cystatin-A; Cystatin-AS; Stefin-A; Stefin A

Clonality

Monoclonal

Clone

2C8

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Cell Biology; Signal Transduction; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

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