Purified Anti-Human CD123 Antibody[HI12H7]
Selected Variant
E-AB-F1340A-01
Size: 25 µg
Product Specifications
Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
Abbreviation
CD123
UniProt
P26951
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD123 protein
Target
IL3R, CD123, IL3RX, IL3RY, IL-3R&alpha, IL3RA, IL3RAY, hIL-3Ra, IL-3 Receptor alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R subunitalpha, IL-3RA, IL-3R-alpha, IL-3Receptoralpha, IL-3Rα, IL-4Receptoralpha, IL-5Receptoralpha, IL-6Receptoralpha, IL-7Receptoralpha, Interleukin-3 receptor subunit alpha
Clonality
Monoclonal
Clone
HI12H7
Conjugation
Unconjugated
Applications
FCM
Field of Research
Cytokine and Growth Factors, Immunology, Signal Transduction, CDs
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
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