Purified Anti-Human CD99 Antibody[HI156]

CD99 is a type I single chain transmembrane protein devoid of N-linked glycosylation sites encoded by the pseudoautosomal gene MIC2. CD99 has an apparent molecular weight of 32 kD and is widely expressed on a variety of tissues. CD99 is highly expressed on thymocytes, T cells, and T cell leukemias and lymphomas. However, it is absent on some B cell lines, fetal B cells, eosinophils, granulocytes and the NK-cell line YT. CD99 is involved in spontaneous rosette formation with erythrocytes and may also be involved in other T-cell and hematopoietic cell adhesion pathways. CD99 has been reported to activate a caspase-independent death pathway in T cells under some conditions. CD99 interacts with a number of proteins including ferritin heavy chain 1, karyopherin beta 1, TRIP13, cyclophilin A, annexin II, and ubiquitin-conjugating enzyme E2H.

MIC2, Protein MIC, T-Cell Surface Glycoprotein E, MIC2Y, MSK5X,12E7, CD99 Antigen, E2 Antigen, Protein MIC2, T-Cell Surface Glycoprotein E2, E2, CD99 molecule, CD99 molecule (Xg blood group) I603, Antigen identified by monoclonal 12E7, Antigen identified by monoclonal antibodies 12E7, Cell surface antigen 12E7, Cell surface antigen HBA 71, Cell surface antigen O13, F21 and O13, MIC 2X, MIC 2Y, MIC2 (monoclonal 12E7), Surface antigen MIC2, T cell surface glycoprotein E2, Y homolog, MIC, HBA,12E, CD99, HBA71, MIC2X