Purified Anti-Human CD20 Antibody[HI20a]
Product Specifications
Background
CD20 is a 297 amino acid (aa) non-glycosylated type III membrane protein that is the founding member of the MS4A tetraspanin protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa sequence identity between human and mouse CD20.
Abbreviation
CD20
UniProt
P11836
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD20 protein
Target
B-lymphocyte antigen CD, Leukocyte surface antigen Leu, MS4A1, CVID5, S7, Bp35, LEU-16, Bp35, Ly-44, B lymphocyte antigen CD20, B Lymphocyte Cell Surface Antigen B1, CD 20, CD20 antigen, CD20 receptor, APY, ATOPY, B-lymphocyte cell-surface antigen B1, Bp 35, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, Fc epsilon receptor I beta chain, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU 16, LEU16, leukocyte surface antigen Leu 16, Ly44, Membrane spanning 4 domains A1, Membrane spanning 4 domains subfamily A member 2, MGC3969, LEU, CVID, B-lymphocyte surface antigen B, Membrane-spanning 4-domains subfamily A member, B1, CD20, MS4A2, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1
Clonality
Monoclonal
Clone
HI20a
Conjugation
Unconjugated
Applications
FCM
Field of Research
CDs, Cancer, Immunology, Stem Cells, Hematopoietic Stem Cell Markers, Tumor-associated antigens
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG2a, κ
Available Sizes
Curated Selection
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