Purified Anti-Rat CD44H Antibody[OX-49]

The OX-49 antibody reacts with the glycoprotein CD44H (also known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes, and at greatly increased levels on T- and B-cell blasts. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However, recent reports indicate that OX-49 antibody cannot detect the CD44v isoform, possibly due to conformational changes in the epitope. CD44 is a cell adhesion receptor, and its ligand, hyaluronate, is a common component of extracellular matrices.

BA-1, CD44 antigen, CD44 molecule, Cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, HUTCH1, Cd44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HAS, PGP-1, Phagocytic glycoprotein 1, CD44 molecule (Indian blood group), CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, Pgp, CD44H, CD44s, H-CAM, Pgp-1