Purified Anti-Human CD40 Antibody[5D12]
Product Specifications
Background
CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62% aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines.
Abbreviation
CD40
UniProt
P25942
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CD40 protein
Target
CDW, CDW40, TNFRSF, Bp50, p50, TNFRSF5, B cell associated molecule CD40, B cell surface antigen CD40, B cell-associated molecule, CD 40, CD40 (protein), CD40 antigen, CD40 antigen (TNF receptor superfamily member 5), CD40 molecule, CD40 protein, CD40 type II isoform, AI326936, GP39, HIGM1, IGM, IMD3, isoform CRA_a, member 5, MGC9013, Nerve growth factor receptor related B lymphocyte activation molecule, OTTHUMP00000031699, OTTHUMP00000031700, TBAM, T-BAM, TNF receptor superfamily member 5, TNR5, TRAP, Tumor necrosis factor receptor superfamily, Tumor necrosis factor receptor superfamily member 5 precursor, B-cell surface antigen CD, Tumor necrosis factor receptor superfamily member, CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, CD40L receptor
Clonality
Monoclonal
Clone
5D12
Conjugation
Unconjugated
Applications
FCM
Field of Research
Hematopoietic Stem Cell Markers, CDs, B Cell Receptor Signaling Pathway, NF-kB Signaling Pathway, Immunology, Stem Cells, Cardiovascular Biology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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