Purified Anti-Human TNF-α Antibody[Adalimumab297.rMAb]
Selected Variant
AN007900P-01
Size: 25 µg
Product Specifications
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell prolifeRation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Abbreviation
TNF-α
Gene ID
7124
UniProt
P01375
Host
Human
Reactivity
Human
Immunogen
Recombinant Human TNF-alpha protein
Target
Tumor Necrosis Factor Ligand Superfamily Member; TNFSF; TNF; DIF; TNF-alpha; TNFA; TNFSF2; TNLG1F; TNF alpha; Cachectin; Tumor Necrosis Factor; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; APC1; APC1 protein; DIF、TNF-alpha、TNFA、TNFSF2; Differentiation inducing factor; Macrophage cytotoxic factor; macrophage derived; member 2; Membrane Form; monocyte derived; soluble form; sTNFA; TNF superfamily; Tumor necrosis factor alpha
Clonality
Monoclonal
Clone
Adalimumab297.rMAb
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Signal Transduction; Cancer; Cardiovascular; Metabolism
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
PBS, pH 7.2. Contains 0.05% proclin 300.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Human IgG1, κ
Available Sizes
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