Purified Anti-Human CD49e Antibody[IIA1]

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to geneRate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

VLA; ITGA; CD49e; FNRA; VLA-5; VLA5A; Integrin alpha 5; ITGA5; CD49 Antigen-Like Family Member E; Fibronectin Receptor Subunit Alpha; Integrin Alpha-5; Integrin Alpha-F; &alpha-5 integrin-n; VLA-5α alpha 5 (fibronectin receptor; alpha polypeptide) ; alpha subunit; Fibronectin receptor; Integrin; Integrin alpha 5 (fibronectin receptor alpha) ; Integrin alpha-5 light chain; ITA5; Very late activation protein 5; VLA5