Purified Anti-Human CD55 Antibody[HI55a]

CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI) -anchored single chain glycoprotein also known as decay-acceleRating factor (DAF) . It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 acceleRates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.

CD55; CR; CROM; DAF; TC; Complement Decay-Accelerating factor; CD 55; CD55 antigen; CD55 Cromer blood group system; CD55 molecule; CD55 molecule (Cromer blood group) ; Cd55a; Complement decay accelerating factor; Cromer Blood Group antigen; Cromer blood group system; Cromer blood group system) ; Daf1; Daf-GPI; Dcay accelerating factor for complement (CD55; Decay accelarating factor 1; Decay accelerating factor (GPI-form) ; Decay Accelerating Factor for Complement; decay accelerating factor for complement (Cromer blood group) ; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form; GPI-anchored; GPI-DAF; isoform CRA_a