Mebrofenin

Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA) . Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function[1][2].

Product Specifications

CAS Number

[78266-06-5]

Product Name Alternative

SQ 26962

UNSPSC

12352200

Hazard Statement

H302-H312-H332

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mebrofenin.html

Purity

99.88

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)CN(CC(NC1=C(C)C=C(C)C(Br)=C1C)=O)CC(O)=O

Molecular Formula

C15H19BrN2O5

Molecular Weight

387.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Matthews R, et al. Tc-99m mebrofenin hepatobiliary scan in obstructive hepatobiliary disease: determining causes with early and late delayed imaging. World J Nucl Med. 2013 May;12 (2) :54-6.|[2]Morandi F, et al. Transsplenic portal scintigraphy using 99mTc-mebrofenin in normal dogs. Vet Radiol Ultrasound. 2007 May-Jun;48 (3) :286-91.|[3]de Graaf W, et al. Transporters involved in the hepatic uptake of (99m) Tc-mebrofenin and indocyanine green. J Hepatol. 2011 Apr;54 (4) :738-45.