PI3Kγ inhibitor AZ2
PI3Kγ inhibitor AZ2 is a highly selective PI3Kγ inhibitor (The pIC50 value for PI3Kγ is 9.3) . PI3Kγ inhibitor AZ2 can be used for the research of inflammatory and immune diseases[1].
Product Specifications
CAS Number
[2231760-33-9]
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pi3kγ-inhibitor-az2.html
Concentration
10mM
Purity
99.25
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=C2C(CN([C@H](C3CC3)C)C2=O)=CC(C4=C(C)N=C(NC(C)=O)S4)=C1
Molecular Formula
C20H23N3O2S
Molecular Weight
369.48
References & Citations
[1]Gangadhara G, et al. A class of highly selective inhibitors bind to an active state of PI3Kγ. Nat Chem Biol. 2019;15 (4) :348-357.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
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