Chlorpyrifos-d10
Product Specifications
UNSPSC Description
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
Target Antigen
Cholinesterase (ChE)
Type
Isotope-Labeled Compounds
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Purity
98.0
Solubility
10 mM in DMSO
Smiles
S=P(OC([2H])([2H])C([2H])([2H])[2H])(OC1=NC(Cl)=C(Cl)C=C1Cl)OC([2H])([2H])C([2H])([2H])[2H]
Molecular Weight
360.65
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
285138-81-0
Available Sizes
Curated Selection
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