Tizoxanide-d4 glucuronide

Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum[1].

Product Specifications

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NC=C([N+]([O-])=O)S1)C2=C(O[C@H]3O[C@@H](C(O)=O)[C@H](O)[C@@H](O)[C@H]3O)C([2H])=C([2H])C([2H])=C2[2H]

Molecular Formula

C16H11D4N3O10S

Molecular Weight

445.39

References & Citations

[1]G Gargala , et al. Efficacy of Nitazoxanide, Tizoxanide and Tizoxanide Glucuronide Against Cryptosporidium Parvum Development in Sporozoite-Infected HCT-8 Enterocytic Cells. J Antimicrob Chemother. 2000 Jul;46 (1) :57-60.