D-α-Tocopherol Succinate

D-α-Tocopherol Succinate (Vitamin E succinate) is an antioxidant tocopherol and a salt form of vitamin E. D-α-Tocopherol Succinate inhibits Cisplatin (HY-17394) -induced cytotoxicity. D-α-Tocopherol Succinate can be used for the research of cancer[1][2].

Product Specifications

CAS Number

[4345-03-3]

Product Name Alternative

Vitamin E succinate

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/d-α-tocopherol-succinate.html

Purity

99.52

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CC1=C2C(CC[C@](C)(O2)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C(OC(CCC(O)=O)=O)=C1C)C

Molecular Formula

C33H54O5

Molecular Weight

530.78

Precautions

H302, H315, H319, H335

References & Citations

[1]Kim SK, et al. The effects of the antioxidant α-tocopherol succinate on cisplatin-induced ototoxicity in HEI-OC1 auditory cells. Int J Pediatr Otorhinolaryngol. 2016 Jul;86:9-14.|[2]Kang TH, et al. Treatment of tumors with vitamin E suppresses myeloid derived suppressor cells and enhances CD8+ T cell-mediated antitumor effects. PLoS One. 2014 Jul 29;9 (7) :e103562.