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IFI16 (CT) Peptide

Product Specifications

Background

IFI16 Antibody: IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer. Increased expression of IFI16 predicts adverse prognosis in multiple myeloma. IFI16 isoforms with cytoplasmic and nuclear locations play differential roles in recognizing invaded DNA viruses. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nuclear sensor IFI16 inhibits the function of Hepatitis B virus covalently closed circular DNA by integrating innate immune activation and epigenetic suppression.

NCBI Gene ID

3428

Swiss Prot

Q16666

Accession Number

Q16666.3

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store ULBP1 peptide at -20˚ C, stable for one year.

Applications Notes

IFI16 (CT) Peptide is used for blocking the activity of IFI16 (CT) Antibody.

NCBI Official Name

Interferon gamma inducible protein 16

NCBI Organism

Homo sapiens

Background Reference 01

Ka et al. Cell Rep. 2021; 37 (12) :110138

Background Reference 02

Huang et al. Pharmacogenomics J. 2021; 21 (4) :520-532

Background Reference 03

Li et al. J Immunol. 2021; 207 (11) :2699-2709

Background Reference 04

Jiang et al. Nat Microbiol. 2021; 6 (7) :932-945

Background Reference 05

Yang et al. Hepatology 2020; 71 (4) :1154-1169

Other Product Names

IFI16 Antibody: Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFNGIP1

Tested Applications

Blocking

Species

Human

Protein ID

118572657

Physical Properties

Liquid

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