IRGB10 (CT) Peptide
Product Specifications
Background
IRGB10 Antibody: IRGB10 is an inferno-inducible protein that is essential for the activation of DNA-sensing AIM2 inflammasome, and contributes to the activation of LPS-sensing caspase-11 and NLRP3 inflammasome. IRGB10 is part of a conserved signaling hub at the interface between cell-autonomous immunity and innate immune sensing pathways. IRGB10 targets cytoplasmic bacteria and compromises bacterial structural integrity. IRGB10 and LIGP2 act together to confer differential susceptibility against Chlamydia infection in mice.
NCBI Gene ID
631323
Swiss Prot
AGY29631
Accession Number
AGY29631
Type
Peptides
Concentration
200 ug/mL
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Shipping Conditions
Blue Ice
Storage Conditions
Store IRGB10 (CT) Peptide at -20˚ C, stable for one year.
Applications Notes
IRGB10 (CT) Peptideis used for blocking the activity of theIRGB10 (CT) Antibody
NCBI Official Name
Predicted gene 12250
NCBI Organism
Mus musculus
Background Reference 01
Man et al. Cell 2016; 167 (2) :382-396.e17
Background Reference 02
Bernstein-Hanley I et al. Proc Natl Acad Sci USA. 2006;103 (38) :14092-14097
Background Reference 03
Miyairi I et al. J Immunol 2007; 179 (3) :1814-1824
Background Reference 04
Coers J et al. J Immunol 2008; 180 (9) :6237-6245
Other Product Names
IRGB10 Antibody: Immunity-related GTPase family member b10, Interferon-gamma-inducible p47 GTPase, Gm12250, OTTMUSG00000005723
Tested Applications
Blocking
Species
Mouse
Protein ID
551032829
Physical Properties
Liquid
Frequently Asked Questions
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