IRGB10 (CT) Peptide

Product Specifications

Background

IRGB10 Antibody: IRGB10 is an inferno-inducible protein that is essential for the activation of DNA-sensing AIM2 inflammasome, and contributes to the activation of LPS-sensing caspase-11 and NLRP3 inflammasome. IRGB10 is part of a conserved signaling hub at the interface between cell-autonomous immunity and innate immune sensing pathways. IRGB10 targets cytoplasmic bacteria and compromises bacterial structural integrity. IRGB10 and LIGP2 act together to confer differential susceptibility against Chlamydia infection in mice.

NCBI Gene ID

631323

Swiss Prot

AGY29631

Accession Number

AGY29631

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store IRGB10 (CT) Peptide at -20˚ C, stable for one year.

Applications Notes

IRGB10 (CT) Peptideis used for blocking the activity of theIRGB10 (CT) Antibody

NCBI Official Name

Predicted gene 12250

NCBI Organism

Mus musculus

Background Reference 01

Man et al. Cell 2016; 167 (2) :382-396.e17

Background Reference 02

Bernstein-Hanley I et al. Proc Natl Acad Sci USA. 2006;103 (38) :14092-14097

Background Reference 03

Miyairi I et al. J Immunol 2007; 179 (3) :1814-1824

Background Reference 04

Coers J et al. J Immunol 2008; 180 (9) :6237-6245

Other Product Names

IRGB10 Antibody: Immunity-related GTPase family member b10, Interferon-gamma-inducible p47 GTPase, Gm12250, OTTMUSG00000005723

Tested Applications

Blocking

Species

Mouse

Protein ID

551032829

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx213198-01 50 µL

Calcium-Binding Mitochondrial Carrier Protein Aralar2 (SLC25A13) Antibody

Ask

View Details

abx213198-02 100 µL

Calcium-Binding Mitochondrial Carrier Protein Aralar2 (SLC25A13) Antibody

Ask

View Details

STJ24478 100 µl

Anti-MAP3K5 antibody

Ask

View Details

MC218551 10 µg

Alg1 (BC011281) Mouse Untagged Clone

Ask

View Details

MBS1475342-01 0.02 mg (E-Coli)

Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)

Ask

View Details

MBS1475342-02 0.1 mg (E-Coli)

Recombinant Francisella tularensis subsp. tularensis Hydroxyacylglutathione hydrolase (gloB)

Ask

View Details