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SARS-CoV-2 (COVID-19) Spike L452R Peptide (Delta Variant)

Product Specifications

Background

SARS-CoV-2 delta variant, a variant of concern (VOC), known as B.1.617.2, was detected in India in October of 2020. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 99% of the cases. This variant carries at least 13 mutations in spike protein across the sub lineages, including L452R, D614G, P681R and K417N, which can increase the affinity to the human ACE2 receptor. Enhanced transmission of the Delta variant was observed globally, which is at least 2.5 times more contagious as the other variants. The Delta variant affects the effectiveness of COVID19 vaccine and is resistant to neutralization to some extent.

NCBI Gene ID

43740568

Swiss Prot

P0DTC2

Accession Number

QHD43416

Type

Peptides

Concentration

200 ug/mL

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Shipping Conditions

Blue Ice

Storage Conditions

Store SARS-CoV-2 (COVID-19) Spike L452R Peptide (Delta Variant) at -20˚ C, stable for one year.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=9463P

Applications Notes

SARS-CoV-2 (COVID-19) Spike L452R Peptide (Delta Variant) is used for blocking the activity of theSARS-CoV-2 (COVID-19) Spike L452R Antibody (Delta Variant)

NCBI Official Name

Surface glycoprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Background Reference 01

Zhang et al. JAMA 2021, 325 (13) : 1324-26.

Background Reference 02

Reardon. Nature 2021.

Background Reference 03

Delphine. Nature 2021, 596 (7871) : 276-280.

Other Product Names

SARS-CoV-2 Spike 156-157EF antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein

Tested Applications

Blocking

Species

SARS-CoV-5

Protein ID

1791269090

Physical Properties

Liquid

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