Chemerin Recombinant Protein

Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1) . It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues.

The lyophilized Chemerin recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Chemerin stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Chemerin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.