I-TAC Recombinant Protein

I-TAC is a 'non-ELR' CXC chemokine that is regulated by interferon and signals through the CXCR3 receptor. I-TAC is chemoattractant for IL-2 activated T cells, but does not affect freshly isolated un-stimulated T cells, neutrophils, or monocytes. Recombinant human I-TAC is an 8.3 kDa protein containing 73 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

The lyophilized I-TAC recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted I-TAC is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing I-TAC recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.