RANTES Recombinant Protein

RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV) . Recombinant murine RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

The lyophilized RANTES recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted RANTES is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing RANTES recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.