C10 Recombinant Protein

Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recombinant murine C-10 is a 10.7 kDa protein containing 95 amino acid residues.

The lyophilized C10 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted C10 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing C10 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.