IGF-BP1 Recombinant Protein
Product Specifications
Background
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, where as nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A) .
NCBI Gene ID
3484
Swiss Prot
P08833
Accession Number
NP_000587.1
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Growth Factors, Immunology, Signal Transduction
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized IGF-BP1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IGF-BP1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IGF-BP1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Insulin-like growth factor binding protein 1
NCBI Organism
Homo sapiens
Other Product Names
AFBP, IBP1, PP12, IGF-BP25, hIGFBP-1, Insulin-like growth factor-binding protein 1, Placental protein 12, IBP-1
Species
Human
Protein ID
4504615
Physical Properties
Lyophilized
Available Sizes
Frequently Asked Questions
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