TWEAK Receptor Recombinant Protein

Product Specifications

Background

TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic "death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein.

NCBI Gene ID

51330

Swiss Prot

Q9NP84

Accession Number

NP_057723.1

Type

Recombinant Proteins

Source

E. coli

Field of Research

Apoptosis

Shipping Conditions

Room Temp

Storage Conditions

The lyophilized TWEAK Receptor recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted TWEAK Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing TWEAK Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

NCBI Official Name

Tumor necrosis factor receptor superfamily, member 12A

NCBI Organism

Homo sapiens

Other Product Names

FN14, CD266, TWEAKR, FN14, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, FGF-inducible 14