FGF-21 Recombinant Protein

FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes. Recombinant human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.

The lyophilized FGF-21 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted FGF-21 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing FGF-21 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.