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CD22 Recombinant Protein

Product Specifications

Background

CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.

NCBI Gene ID

933

Swiss Prot

P20273

Accession Number

NP_001172030.1

Type

Recombinant Proteins

Source

CHO cells

Field of Research

Cancer, Immunology, Stem Cell

Shipping Conditions

Room Temp

Storage Conditions

The lyophilized CD22 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted CD22 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing CD22 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=40-147

NCBI Official Name

CD22 molecule

NCBI Organism

Homo sapiens

Other Product Names

SIGLEC2, SIGLEC-2, SIGLEC2, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM

Species

Human

Protein ID

297374830

Physical Properties

Lyophilized

Available Sizes

Curated Selection

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